The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

BACKGROUND: Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn’s disease (CD). Herein, we experimentally quantified the impact of 6-week supplementation with a commercial sweetener (Splenda; ingredients sucralose maltodextrin, 1:99, w/w) on both the sev...

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Dades bibliogràfiques
Publicat a:Inflamm Bowel Dis
Autors principals: Rodriguez-Palacios, Alexander, Harding, Andrew, Menghini, Paola, Himmelman, Catherine, Retuerto, Mauricio, Nickerson, Kourtney P, Lam, Minh, Croniger, Colleen M, McLean, Mairi H, Durum, Scott K, Pizarro, Theresa T, Ghannoum, Mahmoud A, Ilic, Sanja, McDonald, Christine, Cominelli, Fabio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Original Research Articles–Basic Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950546/
https://ncbi.nlm.nih.gov/pubmed/29554272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izy060
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