Benzo(a)pyrene promotes Hep-G2 cell migration and invasion by upregulating phosphorylated extracellular signal-regulated kinase expression

Benzo(a)pyrene (BaP), a carcinogenic component of cigarette smoke, has been reported to activate extracellular signal-regulated kinase (ERK) in cancer cells. Furthermore, activated ERK is associated with liver cancer cell invasion and metastasis. Therefore, the aim of the present study was to invest...

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Udgivet i:Oncol Lett
Main Authors: Wang, Yadong, Pan, Teng, Li, Li, Wang, Haiyu, Zhang, Ding, Yang, Haiyan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950133/
https://ncbi.nlm.nih.gov/pubmed/29805565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8379
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