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Guanylate cyclase–activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors
Light adaptation of photoreceptor cells is mediated by Ca(2+)-dependent mechanisms. In darkness, Ca(2+) influx through cGMP-gated channels into the outer segment of photoreceptors is balanced by Ca(2+) extrusion via Na(+)/Ca(2+), K(+) exchangers (NCKXs). Light activates a G protein signaling cascade...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949989/ https://ncbi.nlm.nih.gov/pubmed/29549122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001574 |
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