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Advances and Challenges on Management of Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) originate from interstitial cells of Cajal and account for over 5,000 newly diagnosed cases in the United States. The discovery of activated KIT and PDGFRA mutations and introduction of imatinib revolutionized the treatment strategy and opened up the new era o...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Mei, Lin, Du, Wei, Idowu, Michael, von Mehren, Margaret, Boikos, Sosipatros A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949718/
https://ncbi.nlm.nih.gov/pubmed/29868467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00135
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