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Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice

After spinal cord injury (SCI), reconstruction of neuronal tracts is very difficult because an inhibitory scar is formed at the lesion site, in which several axonal growth inhibitors, such as chondroitin sulfate proteoglycans (CSPG), accumulate. We previously found that matrine, a major alkaloid in...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Tanabe, Norio, Kuboyama, Tomoharu, Tohda, Chihiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949560/
https://ncbi.nlm.nih.gov/pubmed/29867458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00446
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