Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias

γδ T lymphocytes are potent effector cells, capable of efficiently killing tumor and leukemia cells. Their activation is mediated by γδ T-cell receptor (TCR) and by activating receptors shared with NK cells (e.g., NKG2D and DNAM-1). γδ T-cell triggering occurs upon interaction with specific ligands,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pistoia, Vito, Tumino, Nicola, Vacca, Paola, Veneziani, Irene, Moretta, Alessandro, Locatelli, Franco, Moretta, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949323/
https://ncbi.nlm.nih.gov/pubmed/29867961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00984
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