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Synaptic adhesion protein ELFN1 is a selective allosteric modulator of group III metabotropic glutamate receptors in trans

Functional characterization of the GPCR interactome has been focused predominantly on intracellular interactions, yet GPCRs are increasingly found in complex with extracellular proteins. Extracellular leucine-rich repeat fibronectin type III domain containing 1 (ELFN1) was recently reported to physi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Dunn, Henry A., Patil, Dipak N., Cao, Yan, Orlandi, Cesare, Martemyanov, Kirill A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948991/
https://ncbi.nlm.nih.gov/pubmed/29686062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722498115
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