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Interdependent and separable functions of Caenorhabditis elegans MRN-C complex members couple formation and repair of meiotic DSBs

Faithful inheritance of genetic information through sexual reproduction relies on the formation of crossovers between homologous chromosomes during meiosis, which, in turn, relies on the formation and repair of numerous double-strand breaks (DSBs). As DSBs pose a potential threat to the genome, mech...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Girard, Chloe, Roelens, Baptiste, Zawadzki, Karl A., Villeneuve, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948970/
https://ncbi.nlm.nih.gov/pubmed/29686104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719029115
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