Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability

The biconcave disk shape and deformability of mammalian RBCs rely on the membrane skeleton, a viscoelastic network of short, membrane-associated actin filaments (F-actin) cross-linked by long, flexible spectrin tetramers. Nonmuscle myosin II (NMII) motors exert force on diverse F-actin networks to c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Smith, Alyson S., Nowak, Roberta B., Zhou, Sitong, Giannetto, Michael, Gokhin, David S., Papoin, Julien, Ghiran, Ionita C., Blanc, Lionel, Wan, Jiandi, Fowler, Velia M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948966/
https://ncbi.nlm.nih.gov/pubmed/29610350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718285115
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