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Lifetime of muscarinic receptor–G-protein complexes determines coupling efficiency and G-protein subtype selectivity
G-protein–coupled receptors (GPCRs) are essential for the detection of extracellular stimuli by cells and transfer the encoded information via the activation of functionally distinct subsets of heterotrimeric G proteins into intracellular signals. Despite enormous achievements toward understanding G...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5948956/ https://ncbi.nlm.nih.gov/pubmed/29686069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715751115 |
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