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Homologous recombination occurs frequently at innate GT microsatellites in normal somatic and germ cells in vivo
BACKGROUND: In somatic cells, homologous recombination (HR) is a rare event caused by eventual DNA double-strand breaks (DSBs). In contrast, germ cells show high frequency of HR caused by programmed DSBs. Microsatellites are prone to DSBs during genome replication and, thereby, capable of promoting...
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| Udgivet i: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5948810/ https://ncbi.nlm.nih.gov/pubmed/29751739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4758-y |
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