Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy

Autophagy is a conserved cellular process that functions as a first-line defense to restrict the growth of invading parasitic bacteria. As an intracellular pathogen, Salmonella (S) Typhimurium invades host cells through two Type III secretion systems (T3SS) and resides in the Salmonella-containing v...

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Vydáno v:Cell Death Dis
Hlavní autoři: Liu, Wei, Jiang, Yuanyuan, Sun, Jing, Geng, Shizhong, Pan, Zhiming, Prinz, Richard A., Wang, Chengming, Sun, Jun, Jiao, Xinan, Xu, Xiulong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948208/
https://ncbi.nlm.nih.gov/pubmed/29752434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0612-z
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