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Validation of ligands in macromolecular structures determined by X-ray crystallography

Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) play a crucial role in structure-guided drug discovery and design, and also provide atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. The quali...

詳細記述

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書誌詳細
出版年:Acta Crystallogr D Struct Biol
主要な著者: Smart, Oliver S., Horský, Vladimír, Gore, Swanand, Svobodová Vařeková, Radka, Bendová, Veronika, Kleywegt, Gerard J., Velankar, Sameer
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947763/
https://ncbi.nlm.nih.gov/pubmed/29533230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318002541
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