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Arteriovenous specification: BMPER and TWSG1 determine endothelial cell fate via activation of synergistic BMP and Notch signaling

Two extracellular BMP modulators, BMPER and TWSG1, act in a pro‐BMP fashion to activate endothelial‐specific members of the TGF‐β/BMP receptor family. Through cross‐talk with the Notch signaling pathways, they are key regulators of downstream Notch targets, including ephrin B2. This adds to our unde...

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Détails bibliographiques
Publié dans:FEBS J
Auteurs principaux: Osmanagic‐Myers, Selma, Rezniczek, Günther A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947552/
https://ncbi.nlm.nih.gov/pubmed/29654706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14439
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