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A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue

The in situ immediate detection of the presence of bacteria in the distal human lung is of significant clinical utility. Herein we describe the development and optimization of a bacterial binding fragment (UBI(29–41)) of the antimicrobial peptide, ubiquicidin (UBI), conjugated to an environmentally...

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Veröffentlicht in:Chem Sci
Hauptverfasser: Akram, Ahsan R., Avlonitis, Nicolaos, Lilienkampf, Annamaria, Perez-Lopez, Ana M., McDonald, Neil, Chankeshwara, Sunay V., Scholefield, Emma, Haslett, Christopher, Bradley, Mark, Dhaliwal, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947527/
https://ncbi.nlm.nih.gov/pubmed/29861935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00960j
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