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Estimation of intrathecal IgG synthesis: simulation of the risk of underestimation

OBJECTIVE: The low level of passively diffused IgG through the blood–brain barrier is sufficient to blur the estimation of intrathecal IgG synthesis (ITS). Therefore, this estimation requires a mathematical calculation derived from empirical laws, but the range of normal values in healthy controls i...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Bonnan, Mickael, Gianoli‐Guillerme, Mariana, Courtade, Henri, Demasles, Stéphanie, Krim, Elsa, Marasescu, Raluca, Dréau, Hervé, Debeugny, Stéphane, Barroso, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945966/
https://ncbi.nlm.nih.gov/pubmed/29761116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.548
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