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Hepatic steatosis associated with decreased β-oxidation and mitochondrial function contributes to cell damage in obese mice after thermal injury

Severely burned patients who are morbidly obese have poor clinical outcomes with aggravated metabolic consequences, a higher incidence of multiple organ dysfunction/failure, and significantly increased morbidity and mortality. The underlying mechanisms of these adverse outcomes are essentially unkno...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Diao, Li, Auger, Christopher, Konoeda, Hisato, Sadri, Ali-Reza, Amini-Nik, Saeid, Jeschke, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945855/
https://ncbi.nlm.nih.gov/pubmed/29748608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0531-z
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