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The LuxS/AI-2 Quorum-Sensing System of Streptococcus pneumoniae Is Required to Cause Disease, and to Regulate Virulence- and Metabolism-Related Genes in a Rat Model of Middle Ear Infection

Objective: Streptococcus pneumoniae colonizes the nasopharynx of children, and from nasopharynx it could migrate to the middle ear and causes acute otitis media (AOM). During colonization and AOM, the pneumococcus forms biofilms. In vitro biofilm formation requires a functional LuxS/AI-2 quorum-sens...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Cell Infect Microbiol
Päätekijät: Yadav, Mukesh K., Vidal, Jorge E., Go, Yoon Y., Kim, Shin H., Chae, Sung-Won, Song, Jae-Jun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945837/
https://ncbi.nlm.nih.gov/pubmed/29780750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00138
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