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Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells

Affective disorders such as major depression and bipolar disorder are among the most prevalent forms of mental illness and their etiologies involve complex interactions between genetic and environmental risk factors. Over the past ten years, several genome wide association studies (GWAS) have identi...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Michels, Susanne, Ganjam, Goutham K., Martins, Helena, Schratt, Gerhard M., Wöhr, Markus, Schwarting, Rainer K. W., Culmsee, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945680/
https://ncbi.nlm.nih.gov/pubmed/29760952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0061-6
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