Humanizing Miniature Hearts through 4-Flow Cannulation Perfusion Decellularization and Recellularization

Despite improvements in pre-clinical drug testing models, predictability of clinical outcomes continues to be inadequate and costly due to poor evidence of drug metabolism. Humanized miniature organs integrating decellularized rodent organs with tissue specific cells are translational models that ca...

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Udgivet i:Sci Rep
Main Authors: Nguyen, Duong T., O’Hara, Matthew, Graneli, Cecilia, Hicks, Ryan, Miliotis, Tasso, Nyström, Ann-Christin, Hansson, Sara, Davidsson, Pia, Gan, Li-Ming, Magnone, Maria Chiara, Althage, Magnus, Heydarkhan-Hagvall, Sepideh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945628/
https://ncbi.nlm.nih.gov/pubmed/29748585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25883-x
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