Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience

International guidelines made RAS (KRAS and NRAS) status a prerequisite for the use of anti-EGFR agents for metastatic colorectal cancer (CRC) patients. Daily, new data emerges on the theranostic and prognostic role of molecular biomarkers; this is a strong incentive for a validated, sensitive, and...

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Pubblicato in:Oncotarget
Autori principali: D’Haene, Nicky, Fontanges, Quitterie, De Nève, Nancy, Blanchard, Oriane, Melendez, Barbara, Delos, Monique, Dehou, Marie-Françoise, Maris, Calliope, Nagy, Nathalie, Rousseau, Emmanuel, Vandenhove, Josse, Gilles, André, De Prez, Carine, Verset, Laurine, Van Craynest, Marie-Paule, Demetter, Pieter, Van Laethem, Jean-Luc, Salmon, Isabelle, Le Mercier, Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945518/
https://ncbi.nlm.nih.gov/pubmed/29755687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25099
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