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Context-specific effects of neurodegenerative disease variants in a model of human microglia
Microglia are emerging as a key cell type in neurodegenerative diseases, yet human microglia are challenging to study in vitro, especially in the large numbers of individuals needed for genetic studies. Here we demonstrate the effectiveness of an in vitro model system of human monocyte-derived micro...
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Publicado no: | Sci Transl Med |
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Main Authors: | , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5945290/ https://ncbi.nlm.nih.gov/pubmed/29263232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aai7635 |
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