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The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

To subvert host defenses, Mycobacterium tuberculosis (Mtb) avoids being delivered to degradative phagolysosomes in macrophages by arresting the normal host process of phagosome maturation. Phagosome maturation arrest by Mtb involves multiple effectors and much remains unknown about this important as...

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Udgivet i:PLoS Pathog
Main Authors: Zulauf, Katelyn E., Sullivan, Jonathan Tabb, Braunstein, Miriam
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945054/
https://ncbi.nlm.nih.gov/pubmed/29709019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007011
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