Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset

T-cell acute lymphoblastic leukemia (T-ALL) is a hematopoietic malignancy originating from T-cell progenitors in which differentiation is blocked at early stages. Physiological expression of specific NKL homeobox genes obeys a hematopoietic NKL-code implicated in the process of lymphopoiesis while i...

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Udgivet i:PLoS One
Main Authors: Nagel, Stefan, Meyer, Corinna, Kaufmann, Maren, Zaborski, Margarete, MacLeod, Roderick A. F., Drexler, Hans G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944955/
https://ncbi.nlm.nih.gov/pubmed/29746601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197194
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