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Phosphorylation-mediated clearance of amyloid-like assemblies in meiosis

Amyloids are fibrous protein assemblies that are often described as irreversible and intrinsically pathogenic. However, yeast cells employ amyloid-like assemblies of the RNA-binding protein Rim4 to control translation during meiosis. Here, we show that multi-site phosphorylation of Rim4 is critical...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Cell
Hauptverfasser: Carpenter, Kayla, Bell, Rachel Brietta, Yunus, Julius, Amon, Angelika, Berchowitz, Luke Edwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944619/
https://ncbi.nlm.nih.gov/pubmed/29738715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.04.001
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