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Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures
Current gene synthesis methods are driven by enzymatic reactions. Here we report the one-pot synthesis of a chemically-ligated gene from 14 oligonucleotides. The chemical ligation benefits from the highly efficient click chemistry approach templated by DNA nanostructures, and produces modified DNA t...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Chem Commun (Camb) |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Royal Society of Chemistry
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944424/ https://ncbi.nlm.nih.gov/pubmed/29662975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc00738a |
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