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The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress

BACKGROUND: Histone deacetylase (HDAC) inhibitors can attenuate acute kidney injury (AKI)-mediated damage and reduce fibrosis in kidney disease models. The aim of the present study was to investigate the effects of the HDAC inhibitor MS-275 on lipopolysaccharide (LPS)-induced AKI and the associated...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Zhang, Haiyue, Zhang, Wenbin, Jiao, Fangzhou, Li, Xun, Zhang, Hong, Wang, Luwen, Gong, Zuojiong
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944402/
https://ncbi.nlm.nih.gov/pubmed/29704392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.906362
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