Effects of Anti-TNFα Treatment on Mucosal Expression of IL-17A, IL-21, and IL-22 and Cytokine-Producing T Cell Subsets in Crohn's Disease

T helper 17 (Th17) cells produce interleukin (IL) 17-A. In addition, Th17 cells produce IL-21 and IL-22. Th17 cells have a disease-promoting role in Crohn's disease (CD). We investigated the effects of anti-TNFα treatment on mucosal gene expression (qPCR) of IL-17A, IL-21, and IL-22 as well as...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Dige, Anders, Magnusson, Maria K., Uhrenholt, Claus, Rasmussen, Tue Kruse, Kragstrup, Tue, Öhman, Lena, Dahlerup, Jens, Agnholt, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944277/
https://ncbi.nlm.nih.gov/pubmed/29853788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3279607
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