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Glial cell line-derived neurotrophic factor (GDNF) attenuates the peripheral neuromuscular dysfunction without inhibiting the activation of spinal microglia/monocyte

BACKGROUND: Peripheral neuromuscular dysfunctions were found in elderly individuals, and spinal microglia/monocyte plays an important role on this process. This study aims to test whether the glial cell line-derived neurotrophic factor (GDNF) could attenuate age-related neuromuscular dysfunction by...

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Detalhes bibliográficos
Publicado no:BMC Geriatr
Main Authors: Xie, Fei, Zhang, Fan, Min, Su, Chen, Jingyuan, Yang, Jun, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944173/
https://ncbi.nlm.nih.gov/pubmed/29743034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12877-018-0796-1
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