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Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo
Activation of swelling-induced Cl(−) current (I(Cl,swell)) during neonatal hypoxia-ischemia (HI) may induce brain damage. Hypoxic-ischemic brain injury causes chronic neurological morbidity in neonates as well as acute mortality. In this study, we investigated the role of I(Cl,swell) in hypoxic-isch...
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| Veröffentlicht in: | Acta Pharmacol Sin |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943910/ https://ncbi.nlm.nih.gov/pubmed/29595192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2018.1 |
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