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The amino acid selected for generating mutant TbpB antigens defective in binding transferrin can compromise the in vivo protective capacity

Haemophilus parasuis is the causative agent of the Glässer’s disease (GD), one of the most important bacterial diseases that affect young pigs worldwide. GD prevention based on vaccination is a major concern due to the limited cross-protection conferred by the inactivated whole cell vaccines used cu...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Guizzo, João Antônio, Chaudhuri, Somshukla, Prigol, Simone Ramos, Yu, Rong-hua, Dazzi, Cláudia Cerutti, Balbinott, Natalia, Frandoloso, Gabriela Paraboni, Kreutz, Luiz Carlos, Frandoloso, Rafael, Schryvers, Anthony Bernard
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943581/
https://ncbi.nlm.nih.gov/pubmed/29743502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25685-1
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