Screen and Verification for Transgene Integration Sites in Pigs

Efficient transgene expression in recipient cells constitutes the primary step in gene therapy. However, random integration in host genome comprises too many uncertainties. Our study presents a strategy combining bioinformatics and functional verification to find transgene integration sites in pig g...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Linyuan, Wang, Yuzhe, Wang, Haitao, Hu, Yiqing, Chen, Jingyao, Tan, Tan, Hu, Man, Liu, Xiaojuan, Zhang, Ran, Xing, Yiming, Zhao, Yiqiang, Hu, Xiaoxiang, Li, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943519/
https://ncbi.nlm.nih.gov/pubmed/29743638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24481-1
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