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Genipin alleviates vascular hyperpermeability following hemorrhagic shock by up-regulation of SIRT3/autophagy

Genipin (GP) is commonly used to treat cardiovascular diseases; however, the protective action of GP against vascular hyperpermeability (VH) has not been reported. We previously reported that intrinsic apoptotic signaling (IAS) is involved in VH following hemorrhagic shock (HS). GP inhibits apoptosi...

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Détails bibliographiques
Publié dans:Cell Death Discov
Auteurs principaux: Shumin, Cai, Wei, Xu, Yunfeng, Li, Jiangshui, Liang, Youguang, Gao, Zhongqing, Chen, Tao, Li
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943516/
https://ncbi.nlm.nih.gov/pubmed/29760950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0057-2
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