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Marinobufagenin inhibits glioma growth through sodium pump α1 subunit and ERK signaling‐mediated mitochondrial apoptotic pathway

Malignant glioma is one of the most challenging central nervous system diseases to treat and has high rates of recurrence and mortality. Current therapies often fail to control tumor progression or improve patient survival. Marinobufagenin (MBG) is an endogenous mammalian cardiotonic steroid involve...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Lan, Yu‐Long, Wang, Xun, Lou, Jia‐Cheng, Xing, Jin‐Shan, Zou, Shuang, Yu, Zhen‐Long, Ma, Xiao‐Chi, Wang, Hongjin, Zhang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943480/
https://ncbi.nlm.nih.gov/pubmed/29582577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1469
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