Trivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis

Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, cur...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cui, Xiaofang, Chang, Linmo, Li, Youwei, Lv, Qianrui, Wang, Fei, Lin, Yaxian, Li, Weiyang, Meade, Jonathan D., Walden, Jamie C., Liang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943350/
https://ncbi.nlm.nih.gov/pubmed/29743640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25652-w
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