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Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1

The maintenance of endoplasmic reticulum (ER) homeostasis is essential for cell function. ER stress-induced pre-emptive quality control (ERpQC) helps alleviate the burden to a stressed ER by limiting further protein loading. We have previously reported the mechanisms of ERpQC, which includes a rerou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kadowaki, Hisae, Satrimafitrah, Pasjan, Takami, Yasunari, Nishitoh, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943263/
https://ncbi.nlm.nih.gov/pubmed/29743537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25724-x
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