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Tissue inhibitor of metalloproteinases 1 enhances rod survival in the rd1 mouse retina

Retinitis pigmentosa (RP), an inherited retinal degenerative disease, is characterized by a progressive loss of rod photoreceptors followed by loss of cone photoreceptors. Previously, when tissue inhibitor of metalloproteinase 1 (TIMP1), a key extracellular matrix (ECM) regulator that binds to and i...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kim, Hwa Sun, Vargas, Andrew, Eom, Yun Sung, Li, Justin, Yamamoto, Kyra L., Craft, Cheryl Mae, Lee, Eun-Jin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942829/
https://ncbi.nlm.nih.gov/pubmed/29742163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197322
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