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Simultaneous lineage tracing and cell-type identification using CRISPR/Cas9-induced genetic scars

A key goal of developmental biology is to understand how a single cell transforms into a full-grown organism comprising many different cell types. Single-cell RNA-sequencing (scRNA-seq) is commonly used to identify cell types in a tissue or organ1. However, organizing the resulting taxonomy of cell...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Spanjaard, Bastiaan, Hu, Bo, Mitic, Nina, Olivares-Chauvet, Pedro, Janjuha, Sharan, Ninov, Nikolay, Junker, Jan Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942543/
https://ncbi.nlm.nih.gov/pubmed/29644996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4124
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