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Inhibiting mesolimbic dopamine neurons reduces the initiation and maintenance of instrumental responding

Mesolimbic dopamine perturbations modulate performance of reward-seeking behavior, with tasks requiring high effort being especially vulnerable to disruption of dopamine signaling. Previous work primarily investigated longer-term perturbations such as receptor antagonism and dopamine depletion, whic...

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Bibliographic Details
Published in:Neuroscience
Main Authors: Fischbach-Weiss, Sarah, Reese, Rebecca M., Janak, Patricia H.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942212/
https://ncbi.nlm.nih.gov/pubmed/29248527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.12.003
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