Profilin 1–mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

Profilin 1–mediated cytoskeletal dynamics regulate platelet β1- and β3-integrin function and turnover. Profilin 1 deficiency in platelets impairs hemostasis and results in a marked protection from arterial thrombosis.

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Stritt, Simon, Birkholz, Inga, Beck, Sarah, Sorrentino, Simona, Sapra, K. Tanuj, Viaud, Julien, Heck, Johannes, Gaits-Iacovoni, Frédérique, Schulze, Harald, Du, Xiaoping, Hartwig, John H., Braun, Attila, Bender, Markus, Medalia, Ohad, Nieswandt, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2018
Assuntos:
Stimulus Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941999/
https://ncbi.nlm.nih.gov/pubmed/29739775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017014001
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