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Mepolizumab in the management of severe eosinophilic asthma in adults: current evidence and practical experience

Eosinophils represent approximately 1% of peripheral blood leukocytes in normal donors and their maturation and differentiation in the bone marrow are mainly regulated by interleukin (IL)-5 [Broughton et al. 2015]. IL-5, a cytokine that belongs to the β common-chain family, together with IL-3 and gr...

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Bibliografische gegevens
Gepubliceerd in:Ther Adv Respir Dis
Hoofdauteurs: Varricchi, Gilda, Bagnasco, Diego, Ferrando, Matteo, Puggioni, Francesca, Passalacqua, Giovanni, Canonica, Giorgio W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941977/
https://ncbi.nlm.nih.gov/pubmed/27856823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753465816673303
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