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Abnormal PITX1 gene methylation in adolescent idiopathic scoliosis: a pilot study

BACKGROUND: The gene of pituitary homeobox 1 (PITX1) has been reported to be down-regulated in adolescent idiopathic scoliosis (AIS), of which the cause has not been well addressed. The abnormal DNA methylation was recently assumed to be an important mechanism for the down-regulated genes expression...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Shi, Benlong, Xu, Liang, Mao, Saihu, Xu, Leilei, Liu, Zhen, Sun, Xu, Zhu, Zezhang, Qiu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941792/
https://ncbi.nlm.nih.gov/pubmed/29743058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-018-2054-2
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