Parallel substrate supply and pH stabilization for optimal screening of E. coli with the membrane-based fed-batch shake flask

BACKGROUND: Screening in the fed-batch operation mode is essential for biological cultivations facing challenges as oxygen limitation, osmotic inhibition, catabolite repression, substrate inhibition or overflow metabolism. As a screening tool on shake flask level, the membrane-based fed-batch shake...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Philip, P., Kern, D., Goldmanns, J., Seiler, F., Schulte, A., Habicher, T., Büchs, J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941677/
https://ncbi.nlm.nih.gov/pubmed/29743073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-0917-8
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