Deletion of c-FLIP from CD11b(hi) Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis

Idiopathic pulmonary fibrosis is a progressive lung disease with complex pathophysiology and fatal prognosis. Macrophages (MΦ) contribute to the development of lung fibrosis; however, the underlying mechanisms and specific MΦ subsets involved remain unclear. During lung injury, two subsets of lung M...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Respir Cell Mol Biol
Main Authors: McCubbrey, Alexandra L., Barthel, Lea, Mohning, Michael P., Redente, Elizabeth F., Mould, Kara J., Thomas, Stacey M., Leach, Sonia M., Danhorn, Thomas, Gibbings, Sophie L., Jakubzick, Claudia V., Henson, Peter M., Janssen, William J.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941310/
https://ncbi.nlm.nih.gov/pubmed/28850249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0154OC
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