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Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

A novel series of substituted 2-thiohydantoin incorporated with benzoimidazole, pyrazole, triazole and/or benzoxazole moieties has been synthesized using (E)-3-[1-(4-bromophenyl)ethylideneamino]-2-thioxoimidazolidin-4-one 1 as the key starting material. The key material 1 also, reacted with an aceti...

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Publicado no:Chem Cent J
Main Authors: Elhady, Heba A., El-Sayed, Refat, Al-nathali, Hamedah S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940965/
https://ncbi.nlm.nih.gov/pubmed/29740713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0418-1
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