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Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts

Connective tissue growth factor (CTGF) associated with transforming growth factor-β (TGF-β) play a pivotal role in the pathophysiology of many fibrotic disorders. However, it is not clear whether this interaction also takes place in GO. In this study, we investigated the role of CTGF in TGF-β-induce...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Tsai, Chieh-Chih, Wu, Shi-Bei, Kau, Hui-Chuan, Wei, Yau-Huei
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940888/
https://ncbi.nlm.nih.gov/pubmed/29739987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25370-3
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