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The effect of high fat diet and metformin treatment on liver lipids accumulation and their impact on insulin action

We sought to determine whether metformin treatment reverses a high-fat diet (HFD)-induced hepatic insulin resistance (IRes) and to identify lipid intermediates involved in induction of liver IRes. The experiments were conducted on male Wistar rats divided into three groups: 1. Control, 2. fed HFD an...

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Publicat a:Sci Rep
Autors principals: Zabielski, Piotr, Hady, Hady Razak, Chacinska, Marta, Roszczyc, Kamila, Gorski, Jan, Blachnio-Zabielska, Agnieszka U.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940807/
https://ncbi.nlm.nih.gov/pubmed/29739997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25397-6
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