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FGF23 Actions on Target Tissues—With and Without Klotho

Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co-receptor that increases the binding affinity of FGF23 for FGFRs. By stimulating FGFR/klotho complexes in the kidney and par...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Richter, Beatrice, Faul, Christian
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940753/
https://ncbi.nlm.nih.gov/pubmed/29770125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00189
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