Intralesional uridine-5′-triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th(1) immune responses and reactive oxygen species production

Leishmania amazonensis is the etiologic agent of cutaneous leishmaniasis, an immune-driven disease causing a range of clinical symptoms. Infections caused by L. amazonensis suppress the activation and function of immune cells, including macrophages, dendritic cells, and CD4(+) T cells. In this study...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Marques-da-Silva, Camila, Chaves, Mariana M., Thorstenberg, Maria Luiza, Figliuolo, Vanessa R., Vieira, Flávia S., Chaves, Suzana P., Meyer-Fernandes, José Roberto, Rossi-Bergmann, Bartira, Savio, Luiz Eduardo Baggio, Coutinho-Silva, Robson
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940633/
https://ncbi.nlm.nih.gov/pubmed/29680937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-018-9606-7
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