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Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to preserve the genome and improve stroke recovery

The past two decades have witnessed remarkable advances in oxidative stress research, particularly in the context of ischemic brain injury. Oxidative stress in ischemic tissues compromises the integrity of the genome, resulting in DNA lesions, cell death in neurons, glial cells, and vascular cells,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Li, Peiying, Stetler, R. Anne, Leak, Rehana K., Shi, Yejie, Li, Yan, Yu, Weifeng, Bennett, Michael V.L., Chen, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940593/
https://ncbi.nlm.nih.gov/pubmed/29128308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.11.011
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